{"id":4375,"date":"2025-04-04T11:42:51","date_gmt":"2025-04-04T09:42:51","guid":{"rendered":"https:\/\/web.infn.it\/TechTransfer\/portfolio_page\/hypoxic-cell-culture-chamber-with-oxygenation-gradient\/"},"modified":"2026-01-16T11:11:18","modified_gmt":"2026-01-16T10:11:18","slug":"hypoxic-cell-culture-chamber-with-oxygenation-gradient","status":"publish","type":"portfolio_page","link":"https:\/\/web.infn.it\/TechTransfer\/en\/portfolio_page\/hypoxic-cell-culture-chamber-with-oxygenation-gradient\/","title":{"rendered":"Hypoxic cell culture chamber with oxygenation gradient"},"content":{"rendered":"<div class=\"wpb-content-wrapper\"><p>[vc_row css_animation=&#8221;&#8221; row_type=&#8221;row&#8221; use_row_as_full_screen_section=&#8221;no&#8221; type=&#8221;full_width&#8221; angled_section=&#8221;no&#8221; text_align=&#8221;left&#8221; background_image_as_pattern=&#8221;without_pattern&#8221;][vc_column][vc_raw_html]W3dwc2VvX2JyZWFkY3J1bWJd[\/vc_raw_html][vc_empty_space][vc_column_text]<\/p>\n<h1>Hypoxic cell culture chamber with oxygenation gradient<\/h1>\n<p>[\/vc_column_text][vc_empty_space][\/vc_column][\/vc_row][vc_row css_animation=&#8221;&#8221; row_type=&#8221;row&#8221; use_row_as_full_screen_section=&#8221;no&#8221; type=&#8221;full_width&#8221; angled_section=&#8221;no&#8221; text_align=&#8221;left&#8221; background_image_as_pattern=&#8221;without_pattern&#8221;][vc_column width=&#8221;2\/3&#8243;][vc_empty_space][vc_column_text]<\/p>\n<div data-draftjs-conductor-fragment=\"{\"blocks\":[{\"key\":\"r67c\",\"text\":\"L\u2019invenzione oggetto di brevetto \u00e8 una camera per la coltura cellulare che lavora in condizione controllata di ossigeno, fino a lavorare in condizione di gradiente di ossigeno. In particolare questa camera, rispetto a quelle commerciali, ha dimensioni ridotte e pu\u00f2 operare in qualsiasi, e risolve anche il problema dell\u2019irraggiamento e della sterilizzazione della camera stessa.\",\"type\":\"unstyled\",\"depth\":0,\"inlineStyleRanges\":[],\"entityRanges\":[],\"data\":{}}],\"entityMap\":{}}\">The invention covered by the patent is a cell culture chamber that operates under controlled oxygen conditions, even under oxygen gradient conditions. In particular, compared to commercial chambers, this chamber is smaller in size and can operate in any position, and also solves the problem of irradiation and sterilization of the chamber itself. <\/div>\n<p>[\/vc_column_text][vc_empty_space][vc_single_image image=&#8221;4376&#8243; img_size=&#8221;full&#8221; qode_css_animation=&#8221;&#8221;][vc_empty_space][vc_column_text]<\/p>\n<h3><span style=\"color: #20415c;\">How does it work?<\/span><\/h3>\n<p>[\/vc_column_text][vc_empty_space][vc_column_text]<\/p>\n<div data-draftjs-conductor-fragment=\"{\"blocks\":[{\"key\":\"597v7\",\"text\":\"La camera oggetto di brevetto pu\u00f2 lavorare in qualsiasi posizione, orizzontale e verticale, grazie a dei film che stando in tensione non permettono lo spanciamento della camera. La presenza di un foro consente lo sfiato e quindi il riempimento con gas. Il flusso del gas \u00e8 turbolento e quindi consente una migliore diffusione. Nella camera ci sono zone di ingresso e di uscita per permettere una migliore diffusione del gas.\",\"type\":\"unstyled\",\"depth\":0,\"inlineStyleRanges\":[],\"entityRanges\":[],\"data\":{}},{\"key\":\"79c0r\",\"text\":\"Le pareti della camera sono fissate con una cornice e quindi possono essere cambiate, a seconda dell\u2019esigenza. Inoltre, sono molto sottili e trasparenti per permettere l\u2019ispezione ottica.\",\"type\":\"unstyled\",\"depth\":0,\"inlineStyleRanges\":[],\"entityRanges\":[],\"data\":{}},{\"key\":\"1o4ia\",\"text\":\"Infine nella versione di camera a gradiente per uso orizzontale si pu\u00f2 riempire il sistema con una certa quantit\u00e0 di terreno di coltura.\",\"type\":\"unstyled\",\"depth\":0,\"inlineStyleRanges\":[],\"entityRanges\":[],\"data\":{}}],\"entityMap\":{}}\">\n<div class=\"Draftail-block--unstyled \" data-block=\"true\" data-editor=\"64c8o\" data-offset-key=\"yhnef-0-0\">\n<div class=\"public-DraftStyleDefault-block public-DraftStyleDefault-ltr\" data-offset-key=\"yhnef-0-0\"><span data-offset-key=\"yhnef-0-0\">The patented chamber can operate in any position, horizontal or vertical, thanks to films that remain taut and prevent the chamber from bulging. A hole allows for venting and therefore filling with gas. The gas flow is turbulent, allowing for better diffusion. The chamber has inlet and outlet areas to allow for better gas diffusion.   <\/span><\/div>\n<\/div>\n<div class=\"Draftail-block--unstyled \" data-block=\"true\" data-editor=\"64c8o\" data-offset-key=\"6fnge-0-0\">\n<div class=\"public-DraftStyleDefault-block public-DraftStyleDefault-ltr\" data-offset-key=\"6fnge-0-0\"><span data-offset-key=\"6fnge-0-0\">The walls of the chamber are fixed with a frame and can therefore be changed as needed. They are also very thin and transparent to allow for optical inspection. <\/span><\/div>\n<\/div>\n<div class=\"Draftail-block--unstyled \" data-block=\"true\" data-editor=\"64c8o\" data-offset-key=\"rkkm-0-0\">\n<div class=\"public-DraftStyleDefault-block public-DraftStyleDefault-ltr\" data-offset-key=\"rkkm-0-0\"><span data-offset-key=\"rkkm-0-0\">Finally, in the gradient chamber version for horizontal use, the system can be filled with a certain amount of culture medium.<\/span><\/div>\n<\/div>\n<\/div>\n<p>[\/vc_column_text][vc_empty_space][vc_column_text]<\/p>\n<h3><span style=\"color: #20415c;\">Applications<\/span><\/h3>\n<p>[\/vc_column_text][vc_column_text]<\/p>\n<ul>\n<li>Biology and Biochemistry;<\/li>\n<li>Toxicology;<\/li>\n<li>Tissue Engineering;<\/li>\n<li>Study of tumor cell growth.<\/li>\n<\/ul>\n<p>[\/vc_column_text][vc_empty_space][vc_column_text]<\/p>\n<h3><span style=\"color: #20415c;\">Advantages<\/span><\/h3>\n<p>[\/vc_column_text][vc_column_text]<\/p>\n<ul>\n<li>small size;<\/li>\n<li>Operational in any position;<\/li>\n<li>Possibility of oxygen gradient;<\/li>\n<li>Material that allows sterilization and irradiation.<\/li>\n<\/ul>\n<p>[\/vc_column_text][\/vc_column][vc_column width=&#8221;1\/4&#8243; css=&#8221;.vc_custom_1702567488600{margin-bottom: 50px !important;background-color: #042a48 !important;}&#8221; el_class=&#8221;.column_details_portfolio&#8221;][vc_column_text]<\/p>\n<h4><span style=\"color: #ffffff;\">ADDITIONAL DETAILS<\/span><\/h4>\n<p>[\/vc_column_text][vc_empty_space][vc_column_text]<\/p>\n<h5><span style=\"color: #8bc9e0;\"><strong>PATENT OWNERS<\/strong><\/span><\/h5>\n<p style=\"color: #fff; font-weight: bold;\">INFN<\/p>\n<p>[\/vc_column_text][vc_empty_space height=&#8221;21px&#8221;][vc_column_text]<\/p>\n<h5><span style=\"color: #8bc9e0;\"><strong>PRIORITY NUMBER<\/strong><\/span><\/h5>\n<p><strong><span style=\"color: #ffffff;\">EP 4520814<\/span><\/strong>[\/vc_column_text][vc_empty_space height=&#8221;21px&#8221;][vc_column_text]<\/p>\n<h5><span style=\"color: #8bc9e0;\"><strong>TECHNOLOGY SECTOR <\/strong><\/span><\/h5>\n<p><strong><span style=\"color: #ffffff;\">Equipment<\/span><\/strong>[\/vc_column_text][vc_empty_space height=&#8221;21px&#8221;][vc_column_text]<\/p>\n<h5><span style=\"color: #8bc9e0;\"><strong>TT CODE<\/strong><\/span><\/h5>\n<p><strong><span style=\"color: #ffffff;\">P_22.106<\/span><\/strong>[\/vc_column_text][vc_empty_space][vc_row_inner row_type=&#8221;row&#8221; type=&#8221;full_width&#8221; text_align=&#8221;left&#8221; css_animation=&#8221;&#8221;][vc_column_inner el_class=&#8221;riga_spazio_progetti&#8221;][\/vc_column_inner][\/vc_row_inner][vc_empty_space][vc_column_text]<\/p>\n<h5><span style=\"color: #8bc9e0;\"><strong>CONTACT US<\/strong><\/span><\/h5>\n<p><strong><span style=\"color: #ffffff;\">For more information about this technology, <\/span><a href=\"mailto:tto@lists.infn.it\"><span style=\"text-decoration: underline;\"><strong><span style=\"color: #ffffff; text-decoration: underline;\">WRITE TO US<\/span><\/strong><\/span><\/a><\/strong>[\/vc_column_text][vc_empty_space][\/vc_column][\/vc_row][vc_row css_animation=&#8221;&#8221; row_type=&#8221;row&#8221; use_row_as_full_screen_section=&#8221;no&#8221; type=&#8221;full_width&#8221; angled_section=&#8221;no&#8221; text_align=&#8221;left&#8221; background_image_as_pattern=&#8221;without_pattern&#8221;][vc_column][vc_empty_space height=&#8221;51px&#8221;][\/vc_column][\/vc_row]<\/p>\n<\/div>","protected":false},"excerpt":{"rendered":"<p>[vc_row css_animation=&#8221;&#8221; row_type=&#8221;row&#8221; use_row_as_full_screen_section=&#8221;no&#8221; type=&#8221;full_width&#8221; angled_section=&#8221;no&#8221; text_align=&#8221;left&#8221; background_image_as_pattern=&#8221;without_pattern&#8221;][vc_column][vc_raw_html]W3dwc2VvX2JyZWFkY3J1bWJd[\/vc_raw_html][vc_empty_space][vc_column_text] Hypoxic cell culture chamber with oxygenation gradient [\/vc_column_text][vc_empty_space][\/vc_column][\/vc_row][vc_row css_animation=&#8221;&#8221; row_type=&#8221;row&#8221; use_row_as_full_screen_section=&#8221;no&#8221; type=&#8221;full_width&#8221; angled_section=&#8221;no&#8221; text_align=&#8221;left&#8221; background_image_as_pattern=&#8221;without_pattern&#8221;][vc_column width=&#8221;2\/3&#8243;][vc_empty_space][vc_column_text] The invention covered by the patent is a cell culture chamber that operates under controlled oxygen conditions, even under oxygen gradient&#8230;<\/p>\n","protected":false},"author":6,"featured_media":4376,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","portfolio_category":[264,252],"portfolio_tag":[],"class_list":["post-4375","portfolio_page","type-portfolio_page","status-publish","has-post-thumbnail","hentry","portfolio_category-life-sciences","portfolio_category-patents"],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v27.5 - 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