PASTA (INFN-CSN5, 2017-2018)

PASTA project, acronym for Production with Accelerator of 47Sc for Theranostic Applications, was financed as Young research grant by CSN5 of INFN for two years (2017-2018). It was dedicated to nuclear cross section measurements on natV and 48Ti targets for 47Sc production, whose results have been also presented in the IAEA CRP no. F22053 focused on Radiopharmaceuticals labeled with new emerging radionuclides (67Cu, 186Re, 47Sc). The enriched metallic 48Ti targets have been manufactured and characterized within the E_PLATE project.

Stacked target used in the PASTA project

Further studies on 47Sc production have been carried out with enriched 49Ti and 50Ti targets during the REMIX project. Results of both PASTA and REMIX projects have also been the core for the INFN Patent “Metodo per produzione di 47Sc ad alta purezza con ciclotroni ad energie intermedie (35 MeV) attraverso un bersaglio multistrato”.

Measurement of the natV(p,x)47Sc, 46Sc nuclear cross sections carried put within the PASTA project
  • More information can be found here:
  • G. Pupillo, A. Fontana, L. Canton, F. Haddad, H. Skliarova, S. Cisternino, P. Martini, M. Pasquali, A. Boschi, J. Esposito, A. Duatti and L. Mou, Preliminary results of the PASTA project (2019) Colloquia: EuNPC 2018, IL NUOVO CIMENTO 42 C 139 doi: 10.1393/ncc/i2019-19139-1 https://www.sif.it/riviste/sif/ncc/econtents/2019/042/02-03/article/89.
  • G. Pupillo, L. Mou, F. Haddad, A. Fontana, L. Canton, New results on the natV(p,x)43Sc cross section: analysis of the discrepancy with previous data (2020) Nuclear Inst. and Methods in Physics Research, B 464: 32-35 doi: 10.1016/j.nimb.2019.11.032
  • G. Pupillo, L. Mou, A. Boschi, S. Calzaferri, L. Canton, S. Cisternino, L. De Dominicis, A. Duatti, A. Fontana, F. Haddad, P. Martini, M. Pasquali, H. Skliarova, J. Esposito, Production of 47Sc with natural vanadium targets: results of the PASTA project (2019) Journal of Radioanalytical and Nuclear Chemistry 297(3) doi: 10.1007/s10967-019-06844-8 https://link.springer.com/article/10.1007/s10967-019-06844-8
  • L. De Nardo, G. Pupillo, L. Mou, D. Furlanetto, A. Rosato, J. Esposito and L. Meléndez-Alafort, Preliminary dosimetric analysis of the production of 47Sc through natV(p,x)47Sc cyclotron irradiation Physics in Medicine and Biology (2021) doi: 10.1088/1361-6560/abc811 https://pubmed.ncbi.nlm.nih.gov/33480361/
  • F. Barbaro, L. Canton, M.P. Carante, A. Colombi, L. De Dominicis, A. Fontana, F. Haddad, L. Mou, G. Pupillo, New results on proton-induced reactions on Vanadium for 47Sc production and the impact of level densities on theoretical cross sections, Physical Review C (2021) arXiv:2107.13773, doi: 10.1103/PhysRevC.104.044619 https://journals.aps.org/prc/abstract/10.1103/PhysRevC.104.044619