In situ measurement of radiation damage caused by ionizing particles

The present invention proposes a methodological solution for the real-time characterization of the radiation damage released locally by the passage of ionizing charged radiation in biological samples, the relative monitoring of the evolution of the biological system and feedback for possible automated interventions to the system itself.

How does it work?

It is an innovative solution to interface two instruments (magnetic spectrometer, and biological inspection suite) through a control and data acquisition system. It also allows monitoring of the growth chamber (B.I.) both in continuous and activation mode (when the charged particle passes through the magnetic spectrometer). These two modes make it possible to measure in real time the radiation damage caused by a single charged particle, identify the trace in biological samples, and monitor the short- and long-term response of the biological system.

Applications

• Fundamental research in space (astrobiology and space exploration);
• Specific applications (understanding the mechanisms of radiation damage in space, knowledge to enable manned space exploration);
• Nuclear medicine.

Advantages

• It allows in situ and real-time measurement of radiation damage in biological samples, even in complex environments with ionizing radiation (e.g. environments with space radiation);
• Information on the responses of the biological sample to ionizing radiation, with the possibility of automated intervention by injecting a solution into the growth chamber via the central control system.